Soan attempt was made to evaluate their antioxidant activity. Antioxidant activity of hemidesmus indicus pdf the methanolic extract of hemidesmus indicus l asclepiadaceae roots was found to inhibit lipid peroxidation and scavenge hydroxyl and superoxide. Screening of phytochemical and antibacterial activity of. Antioxidant and antihyperlipidemic activity of hemidesmus indicus in rats fed with highfat diet suganya venkateshan, 1 vetriselvan subramaniyan, 2, velmurugan chinnasamy, 3 and sarath chandiran 4. Simarouba glauca also called bitter wood, paradise tree and lakshmi taru 24, belongs to order sapindales, family simaroubaceae, genus simarouba and species glauca. These plants have a wide use in traditional system of medicine.
Evaluation of antioxidant properties of root bark of hemidesmus. Hemidesmus indicus possesses phytochemicals responsible for its antioxidant and choleretic activity. Asclepiadaceae is a well known drug in ayurveda system of medicine. The phytochemical constituents of methanolic extract of h. Jul 22, 2019 the compound 2hydroxy 4methoxy benzoic acid has antivenum and antioxidant properties alam and gomes, a. Hemidesmus indicus, commonly known as anantmul, possesses various pharmacological activities including antiinflammatory activity. Antioxidant, nitricoxide, superoxide, lipidperoxidase. Determination of antimicrobial, cytotoxic and antioxidant. The antioxidant property of roots of hemidesmus indicus l. Caulogenic ability of the nodes decreased with increasing maturity. Aug 12, 2019 antioxidant activity of hemidesmus indicus pdf the methanolic extract of hemidesmus indicus l asclepiadaceae roots was found to inhibit lipid peroxidation and scavenge hydroxyl and superoxide. The antioxidant and antihepatotoxic activities of 50% aqueous ethanolic extract of hemidesmus indicus r. The aqueous extract of whole plant of hemidesmus indicus was showed significant free radical scavenging activity than that of standard.
Antioxidant and antihyperlipidemic activity of hemidesmus indicus ajp, vol. Br article pdf available in journal of ethnopharmacology 8723. The aim of the study was to evaluate the antioxidant, hypoglycaemic and hypolipidemic potential of methanolic extract of roots of hemidesmus indicus hie in streptozotocin stz induced diabetic mice. The present study is designed to investigate antiinflammatory effect of ethanolic extract of hemidesmus indicus eehi on rats and mice. Some earlier works have shown antioxidant activity of a few medicinal plants from this group such as hemidesmus indicus, gymnema sylvestre, calotropis procera and tylophora indica. Evaluation of phytochemical composition and antioxidative. The prevalence of metabolic diseases such as obesity and metabolic syndrome is.
Pharmacological activity antioxidant activity in the study conducted by ravishankara and coworkers methanolic extract of hemidesmus indicus roots showed a concentrationdose dependent inhibition of 1, 1diphenyl2picryl hydrazyl dpph radical, superoxide radicals and moderate nitric oxide scavenging activity. Hemidesmus indicus root extract, purification and characterization the plant hemidesmus indicus root was collected commercially from ms united chemicals and allied products, kolkata, india and was identified by prof n paria, department of botany, university of calcutta. The antioxidant properties of free and encapsulated root extract were determined by dpph, superoxide and hydroxyl radical scavenging assays. These in vitro assays indicate that the extract contains constituents that can be a significant source of natural antioxidant 12. Cell culture derived hemidesmus indicus in the prevention of hypercholesterolemia in normal and hyperlipidaemic rats. Research article open access phytochemical profiling and in. In the present study, antioxidant activity of methanolic extract. Antioxidant activity of roots of hemidesmus indicus. The order of antioxidant potential according to ftc assay was found to be highest in plumbago zeylanica followed by holarrhena antidysenterica, acorus calamus and hemidesmus indicus. The root bark also possess antioxidant activity ravishankara et al. Antioxidant activity of roots of hemidesmus indicus request pdf.
Jun 24, 2019 antioxidant activity of terminalia arjuna pdf pdf the present investigation was carried out to evaluate the antioxidant nature of ethanolic extract of terminalia arjuna bark eeta on. Antioxidant and antihyperlipidemic activity of hemidesmus. Ccl 4 and paracetamol induced hepatic damage can be cured upto an extent too by h. Institute of pharmaceutical education and research, near gh6, sector23, gandhinagar 382 023, india. Hie was analyzed by lcms to determine its phytochemical composition. The invitro antioxidant activity of hie was analyzed through inhibition of free radical scavenging activity frsa, total antioxidant power tap and reducing. The traditional indian medicine and the use of plant drugs against various diseases receive considerable attention nowadays. Jan 01, 2002 read evaluation of antioxidant properties of root bark of hemidesmus indicus r.
Academic sciences asian journal of pharmaceutical and. The antioxidant activity of the plant extracts was tested using two methods. Assessment of antioxidant potentials of free and bound phenolics of. Hemidesmus indicus benefits, usage, dose, side effects. Multitarget activity of hemidesmus indicus decoction against. Medicinal plants, phytochemicals, antibacterial activity, vetiveria zizanioides l. The present study showed that an aqueous extract of hemidesmus indicus roots has potent antigenotoxic activity against cisplatininduced cytogenetic damage and is cytotoxic. Preliminarily phytochemical screening and in vivo safety.
Hemidesmus indicus journal of applied pharmaceutical science. The antiinflammatory effect is investigated employing acute anti. The results of the study indicate that hemidesmus indicus root extract possesses antihyperglycemic, antioxidant and antidyslipidemic activity. Buchanania axillaris, hemidesmus indicus, rhus mysorensis, phytochemical profile, antioxidant activity, anticholinesterase activity, antidiabetic activity background alzheimers disease ad is a chronic neurodegenerative irreversible brain disorder that affects daily living through memory loss and cognitive impairment 1, 2. Pharmacognostical and phytochemical studies of hemidesmus. In vitro antioxidant and antithrombotic activity of hemidesmus indicus l r. Jan 17, 2020 studies on steroids in cultured tissues and mature plant of h. In the present study, antioxidant activity of methanolic extract of h.
Hemidesmus indicus, phytochemical constituents, pharmacological actions, toxicity. The root extract of hemidesmus indicus was found to scavenge the superoxide generated by photoreduction of riboflavin. Encapsulated poly lactidecoglycolide plga nanoparticles. Request pdf antioxidant activity of roots of hemidesmus indicus the antioxidant property of roots of hemidesmus indicus l. Herbal medicines still remain the mainstay of about 7075% of the world population, mainly in developing countries for primary health care because of better compatibility, cultural acceptability and lesser side effects. Antioxidant activity of some common medicinal plants. Evaluation of antioxidant properties of root bark of. The concentration needed for 50% scavenging of superoxide was found to be 73. A number of indian medicinal plants have been used for thousands of years in a traditional system of medicine. Pdf in vitro antioxidant and antithrombotic activity of. Studies on steroids in cultured tissues and mature plant of h. Antioxidant activity of terminalia arjuna pdf pdf the present investigation was carried out to evaluate the antioxidant nature of ethanolic extract. Evaluation of synergistic activity of hemidesmus indicus and. Antioxidant properties and principal phenolic phytochemicals.
Plastic surgery, couching a form usess cataract surgerypuncturing to release fluids in abdomen, treatment of anal fistulas, treating fractures, amputations, cesarean sections and. The objective of the present investigation was to evaluate the invitro antioxidant activity of total phenolics and flavonoids compounds extracted from the whole plant of hemidesmus indicus. Morphological and phytochemical characterisation of different accessions of hemidesmus indicus l. Methanol hirm and aqueous hira extracts of the drug were. Hemidesmus indicus is an important medicinal plant and extensively used in ayurvedic and unani system of medicine. In ayurveda system of medicine, it is widely used in the treatment of oligospermia, gastritis, anorexia, menorrhagia etc. The results are comparable with glyclazide, an oral standard hypoglycemic drug. The altered levels of lipid profile were reverted back to near normalcy upon the extract treatment. The present study was conducted to evaluate antimicrobial, cytotoxic and antioxidant activities in 85% ethanol and hot water extracts of root and leaves of h. Antioxidant and antihepatotoxic activities of hemidesmus. Hemidesmus free phenolic fraction hdfp and hemidesmus bound phenolic fraction hdbp have been isolated from h. A voucher specimen has been deposited at the department of. The ftc method was used to measure the amount of peroxide at the beginning of the lipid peroxidation, in which peroxide reacts with ferrous chloride and form ferric ion. Studies have also reported larvicidal potential of hemidesmus indicus root extracts 10.
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